Suboxone
Suboxone® combines buprenorphine and naloxone to reduce withdrawal symptoms while protecting against misuse.
Like Sublocade®, Brixadi® is a buprenorphine extended-release injection for subcutaneous administration. It’s designed to treat individuals suffering from moderate to severe opioid use disorder. Brixadi® was approved by the FDA in 2023 as an alternative treatment to other single-dose buprenorphine treatments. Like Suboxone® and Sublocade®, Brixadi® reduces withdrawal symptoms, the likelihood of relapse, and the cravings associated with OUD.
Buprenorphine interacts with the same neuroreceptors in the brain that opioids bind with. It does a better job of binding with neuroreceptors than opioids do, so it blocks the pathways and prevents the abused opioids from targeting them. Additionally, buprenorphine does not provide euphoria the same way opioids do, so there’s no risk of trading one addiction for another.
Brixadi® comes in weekly and monthly doses. Depending on your needs, your doctor may place you on weekly doses if you feel cravings are returning near the end of a monthly dose. The variability in dosing also means your Brixadi® treatments can be adjusted to suit your tapering needs as your treatment progresses.
If you struggle with higher doses of injectable buprenorphine treatments, Brixadi® may provide relief.Brixadi® offers doses in various strengths to allow patients of all tolerance levels to receive the treatments they need.
With other buprenorphine treatments, you may experience soreness of the injection site after repeated doses. Brixadi® solves this issue by maintaining effectiveness from multiple recommended injection sites. It can be administered in the buttock, thigh, abdomen, or upper arm (after the first four doses).
Brixadi® works the same way as other buprenorphine injection treatments. This means that individuals who have already initiated treatment with other injectable or oral buprenorphine medication can easily switch to Brixadi® with little difficulty.
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